Medicare

For Medicare beneficiaries, Medicare covers COVID-19 vaccines through Medicare Part B. Claims for COVID-19 vaccines must be submitted to Medicare Part B Administrative Contractors (MACs) or Medicare Advantage.

Health care providers should code for the vaccine product administered and the related COVID-19 vaccine administration.

Based on your inputs:

Spikevax 0.25 mL dose
Medicare

Start Over

CPT Code - Vaccine Product

Use the CPT code for the vaccine and dose administered.

Spikevax® (COVID-19 Vaccine, mRNA) 2025-2026 Formula0.25 mL Prefilled Syringe

VACCINE CODE:

CPT 91321

VACCINE DESCRIPTOR:

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) vaccine, mRNA-LNP, 25 mcg/0.25 mL dosage, for intramuscular use.

CPT Code - Vaccine Administration

Use CPT code 90480 for administration of all COVID-19 vaccinations.

ADMINISTRATION CODE:

CPT 90480

ADMINISTRATION DESCRIPTOR:

Immunization administration by intramuscular injection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease [COVID-19]) vaccine, single dose.

Additional Codes

ICD-10

DIAGNOSIS CODE:

Z23 Encounter for Immunization

DIAGNOSIS DOCUMENTATION:

Document the patient's situation and use consistent with the FDA authorization and CDC guidelines.

CVX

CVX CODE:

311

CVX DESCRIPTOR:

SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, 25 mcg/0.25 mL dose.

Used for registries as required.

For more details, visit our Frequently Asked Questions page.

Please see the Spikevax® 2025-2026 Formula Prescribing Information.

Spikevax 2025-2026 Formula Prescribing Information

The coding and billing information contained in this digital tool is provided as a resource and every effort is made to ensure the accuracy of this information. Appropriate coding and billing for healthcare services are the provider's responsibility and should always be based on the patient's clinical condition, services provided, and current payer guidelines